So, nicotine leads to the up-regulation of an enzyme I wont bother to name that is beneficial to how the muscles can utilize fat for energy and how the fat cells refrain from just taking more fat in as storage. Airplane versus subway? But you should be in the habit of listening to people talk about stuff that you dont agree with. So it might be another totally new way to tap benefit above and beyond the nighttime sleep. As an Amazon Associate, Freakonomics may earn commissions from qualifying purchases made through links on this site. I said, No, no, no. So the other night here is a funny story, because it will come across that my daughter lives a tortured life she really does enjoy this stuff. The first two are simple: Diet and exercise. Its also the one that seemed the most conflicted. Its not about exercising more, especially as he gets older. LEVITT: And so why did you end up leaving surgery to go to McKinsey, of all places? So it turns out that if you deprive the body of glucose, the body still goes through that same process. Its just so hard to quit stuff. So the former is one molecule of something called glucose and one of fructose bound together. It is the one thing that makes all three of those worse, and, in its most extreme state, its Type 2 diabetes. scan a couple days later. So I think when you say sugar, what you mean is added sugar. Residency didnt seem very merit-based. Lets dive in! I mean, I probably wish I had been a bit more introspective a bit sooner. LEVITT: The set of things hes done to his body over time, in the spirit of self-experimentation, are mind-blowing. So this just reinforced in me that, youre not immortal. , where his research focused on immune-based therapies for melanoma. My practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). Peter's current diet can simplified into 3 "rules": Time Restricted Feeding Avoid Sugars, High Fructose Corn Syrup & Junk Food No Restriction on Healthy Starches and Vegetables 1) Time Restricted Feeding At the low end, Peter fasts between 14 - 16 hours each day, and at the high end, he fasts between 20 - 22 hours. Theres an, Tim is an early-stage investor and author of five #1 New York Times bestsellers. You have to have a second project which youve actually done, but you pretend that you havent done it. That was painful to watch. And I had all the time in the world. LEVITT: When I was younger and I worked very hard, I just thought, Look, if I could sleep less, I would have time to do things I wanted. And so I read the literature and I embarked on a sleep experiment. And when it comes to naps, Dr. Peter says theyre fine, as long as they dont disrupt your sleep at night. Peter Attia is among the most brilliant people I've ever met, and he's succeeded in packing a life's worth of insights into this book. In Part One, we talked about how mental health affects longevity, daily practices you can do to live a longer and healthier life, and all the details on Type 2 diabetes. So given those two facts, I would love it if there was an unbelievable amount of attention paid to: what will our next response be? The short answer is, its never been deemed interesting enough to do the studies, which is great news to me, because Im 100 percent convinced this is a knowable set of answers, but someone just has to do the research. The only sad part is my dad said a few days ago, Yeah, the last person I grew up with and I was friends with, they died. The second thing I would say is: really do not consider sunk costs in your career. So, Ive done a lot of different things and that makes me a master of nothing. Dr. Peter Attia is a physician focusing on the applied science of longevity. So shes like, lets watch M.S.T.3.K. And that, to me, is where I get shocked at what Id call the failure of medicine in this dimension to provide us with the answers that, if we had known a lot more about other kinds of infectious diseases, we probably could have been a lot smarter. So that comes in mostly two forms in the United States, which is sucrose, or table sugar, which is that white granular powder, or high fructose corn syrup, which is a syrupy liquid approximation of that. And to me, we want to minimize that gap, right? It started very early. We won. Dr. Attia believes we must replace this outdated framework with a personalized, proactive strategy for longevity, one where we take action now, rather than waiting. And my glucose level is very low. One half of all Americans are on that spectrum. Dr. Peter Attia. We only accept comment from posters who identify themselves. You can really imagine the matrix of studies that needs to be done, which says, O.K., what does transmission look like inside versus outside? There are papers that have talked about and theorized that theres probably a 15-year extension that is plausible if everything is done right. Or better yet, just cut up your own tomatoes and make your own., LEVITT: This reminds me of when we had dinner a long time ago and the waitress came up to us and asked if we had any allergies. for Dr. Peters definition of greatness, so for now, Ill leave you with one final piece of wisdom: There are people out there who have so many genetic things working against them, that theyll be lucky to make it to 80. Too often, it intervenes with treatments too late to help, prolonging lifespan at the expense of healthspan, or quality of life. I also had an additional conversation with Kevin Hall, PhD, one of the key researchers NuSI . ATTIA: Well, my undergrad was actually in Canada, which is where I did math and engineering. And so its okay to be an engineer and then to be a surgeon and then to be a McKinsey guy and then to be a nutrition guy and then to be a this guy and a that guy. To improve sleep, Peter Attia takes phosphatidylserine, magnesium and a supplement called Doc Parsley's Sleep Remedy (a company in which Attia invested), comprising of vitamin D, niacin, magnesium (150 mg), and a blend of tryptophan, GABA, phosphatidylserine, theanine, 5-HTP and melatonin. Every time I go to an academic seminar, Im going to bring two pieces of Nicorette gum. Do you recognize that in yourself? But I just decided death would be welcome. [6] As his residency drew to a close, Attia joined the consulting firm McKinsey & Company in the Palo Alto office as a member of the Corporate Risk Practice and Healthcare Practice. Both of them are funded by the Arnold Foundation, with substantial ties to animal agriculture industry lobbying. Have any hacks how to do? He is an ultra-endurance athlete, compulsive self-experimenter, and one of the most fascinating human beings I know. My guest today is physician Dr. Peter Attia. Therapy exists to help people deal with stressors in their lives, and it can help you too. LEVITT: So can you talk about ketosis a little bit and what that means? Part 1. They get their money from Congress. And at the time, what they said I dont know if they still say it was that if you just limit yourself to something like three hours of sleep, you get used to it and your body adjusts to it. Marion Nestle notes the Arnold's working relationship with a National Restaurant . When it comes to chronic and life-threatening diseases, Dr. Peter said it comes down to three major things: So the big three are, in order, atherosclerotic disease so thats vascular disease, meaning heart disease and stroke. today! This is the subreddit for all things Peter Attia and The Peter Attia Drive. So I just generally say try not to eat too much before bed. You remember what Im talking about? Including a link to relevant content is permitted, but comments should be relevant to the post topic. And theres no getting around that. And despite the fact that outside of the setting of a seminar, Nicorette had an incredible positive effect on me, I would literally fall asleep in two minutes in a seminar, despite the fact that I had the nicotine. I want to be able to pull myself out of a pool where theres a one-foot gap between the water and the curb. But I love that about you, that youre willing to change your mind. He explains the evolutionary drive to go from single-cell to multicellular life and unpacks the four different types of cell-based therapies and the problems they are attempting to solve. So, I think it puts N.I.H. And if people say to me, sometimes hey man, Give me one piece of dietary advice, Id be like, Just start reading labels. And a guy who was one weight class above me and quite frankly, at that point, a better fighter I mean, he just landed a right cross on the side of my head that at the time, I didnt think anything of. ATTIA: I actually this is probably one that has changed less than most in the past decade. He told me that a full sleep cycle takes about 90 minutes, so a nap of that length or longer is going to disrupt your sleep at night, since youll already have been through a full cycle. You went to McKinsey. How does our mental health affect our longevity? According to Tools of Titans, Attia takes 600 to 800 mg per day of magnesium, alternating between mag sulfate and mag oxide. For one thing, we can avoid looking at our electronics before bed. December 9, 2022, Designed by Elegant Themes | Powered by WordPress. and . He is of Coptic Egyptian descent. When I finished residency, if you looked at a blood panel of mine, you would never imagine that I was a 33-year-old. I mean, this is not an unethical thing to do. He is willing to entertain any hypothesis. Glucose is such an important molecule for energy that if we were to go more than about a day and a half without eating, we would begin rapidly destroying our muscle mass in an effort to produce enough glucose to satisfy our brain, which would further impair our ability to forage for food. So you went to Stanford and got your medical degree there and then you did your residency at Johns Hopkins. ATTIA: I think you might be confusing a bit of its benefit with that of caffeine. But I have to say, hes also completely, totally insane. I am absolutely in the process of rewriting it, and that is my intention. And I now realize in retrospect that was almost assuredly primarily being contributed by the lack of sleep. Note this may include abusive, threatening, pornographic, offensive, misleading or libelous language. So, if we can stop eating a few hours before bedtime, well get better sleep, our bodies will process the glucose we consume, and we can avoid Type 2 diabetes. ATTIA: Totally my favorite thing on the planet. When we start to experience those mental health issues, we die in a sense. We would like it such that, when you die, its really your first encounter with death of any form. , So the big three are, in order, atherosclerotic disease so thats vascular disease, meaning heart disease and stroke. To me the more important question, Steve, and the one I spend more time thinking about, is: what do you do next time around? Theres days I guess I am. It also has a significant effect in terms of fat oxidation. Additionally, Dr. Peter is an advisor to and/or investor in the following companies: Virta Health, Hu Kitchen, Oura Health Oy, Magic Spoon Cereal, Inevitable Ventures, Salutoceuticals, Dexcom, and Supercast. And I want you to interrupt me every time you have a question.. And actually, my model ended up working really well, but I was basically threatened that Id be fired if I ever did it again. So autophagy is a very important process for preventing cancer. And so for six months, Ive been doing something that was probably a really bad idea as well. What outcome data are there to show that going above 140 mg/dL in a normal glucose excursion is harmful? How do we know if we have Type 2 Diabetes? But thats not the only thing we can do. If anybody knew how bad I was at this, it would be embarrassing., Ill give you one example. And better? Ive never really experienced nicotine. He is well . That sort of irked me. And I think the people who are luckiest and I put myself in that category hit local minima, recognize theyve hit a local minima, but not so much damage has been done that they cant get out of it. So I know Ive got the time to get better and better. These things have a significant impact on our lives and on our families so how can we stay healthier longer? LEVITT: And I asked you, Well, how do you know when its time to stop working out? You said, Either when I lose consciousness or when I piss or crap myself, thats when I decide Ive worked out hard enough.. We talk once every six months or four months. Here we fans discuss the cutting edge of longevity science, the latest episodes, and anything we'd like to see/feedback for the future of the podcast. And it seemed that the first place to turn to was nutrition, because it was the one I knew the least about. . What Happened To Peter Attia. I really enjoy his take on things, his clarity, the brilliant guests he has on, and how out of my depth he is.. And they have totally different mechanisms. And they mightve spent the last 20 of those years in an unbelievable state of misery. Those three effectively make up three quarters of deaths of people who dont smoke. , Theres one disease, which is not really thought of as a disease, but I think of it as a continuum that is the foundation upon which all of those sit. I know Im inspired to increase my healthspan in addition to my lifespan, and I hope you are too! ATTIA: Correct. Autophagy is, as its name implies auto is self, phagy is eating so its when these cells eat themselves. So thats called starvation ketosis. But the probability, Steve, that you or I may get the rest of our lives without another pandemic must be viewed as exceedingly small. Theres days when I think technologys going to solve all of our problems. Comments including unnecessary profanity will be deleted. Its complicated because there are lots of reagents that go into that type of testing and we dont control the origin of each of those reagents. And when my daughter was born, I ended up getting a type of medical test that had a finding that no one in their mid-thirties should have. ATTIA: I mean, look, Steve, that is a million dollar question. Our staff also includes Alison Craiglow, Greg Rippin, and Corinne Wallace; our intern is Emma Tyrrell. Dr. Peter earned his M.D. And its a finding that basically predicts early onset of cardiovascular disease, which shouldnt have been a surprise to me because the list of men in my family who have died of cardiovascular disease is pretty long. In fact, Dr. Peter recommended to stop eating about three hours before bedtime. And while learning to manage stress and overcome trauma may not be the only thing it takes to prevent Type 2 diabetes, it will definitely increase your odds of staying healthy longer. It showed I had cerebral contusions. Its a bit of luck and its having really good people around me who are really patient, who have been able to help nurture me back to a new way of thinking about life that is unrecognizable compared to the ethos that was 10 years ago. makes a complete mockery of what sexual harassment is and is not. Dr. Attia is a huge proponent of supplementing with magnesium. And to this day, we still respect each other greatly. So you took more or less the same approach to academics that you took to boxing. It is the one thing that makes all three of those worse, and, in its most extreme state, its Type 2 diabetes. So I think the whole boxing thing came from an insecurity. He is the Co-founder and Chief Medical Officer of the fasting app. And thats important, but just as important is our mental health. in mechanical engineering and applied mathematics. How many other concussions I had, I dont know. By implication, it cannot be used to make nutrition recommendations. Were living to reach older and older ages than ever before, which is great. He also receives speaking honorariums from organizations, including hospitals and health-related businesses, when he is asked to speak on longevity, metabolic-related topics, athletic performance, and his personal experience working in medicine. You sometimes need that distance from something. Dr. Peter says there are four main ways to do it. Were you a good boxer? And the ability to quit or not quit becomes a very high-water mark to separate those people out. Your podcasts are like a massive gift to humanity. ATTIA: I dont know. So lets say youre someone whos only going to get five and a half hours of sleep at night, which for virtually everyone is still suboptimal. Post a screenshot of the episode along with your biggest takeaways on Instagram, and make sure to tag Dr. Peter, Stay tuned for Wednesdays episode Part 2 of my interview with Dr. Peter Attia! And tell us about the longest period of time you ever spent in ketosis. LEVITT: But when you say risk, you talk about risk of wasting the money? But I tried to build a mathematical model to address a problem in the I.C.U. But it also comes with letting go of a bunch of stuff, too. And I ended up having a C.T. And also, what hes going to talk about in this documentary is really complicated. Hes playing the long-game and working hard to maintain the strength and overall good health hell need to continue living an active and fulfilled life even when hes over 100 years old. When it comes to reversing the effects of Type 2 diabetes and preventing further chronic health problems, sleep is essential. And I will say, hes one of the few people who when he tells me to do something, I just do it. In addition to being an accomplished physician, Dr. Peter is also a successful businessman. Whats so good about being in ketosis? Studying studies: relative risk vs. absolute risk. Apparently Peter and his buddy Gary Taubes just love themselves some crappy pseudoscience. And when I was applying for my first grant, I went to the senior people around the M.I.T. LEVITT: Thats intense. I have used CGM extensively as a non-diabetic and correspondingly have personal experience; I am familiar with the literature cited, have considered it at great length, and have been communicating critically about the use of CGM for non-diabetics for more than a year (and warning people that it is a waste); I have followed Peter Attias career for nearly a decade, have listened to almost all of his >100 podcast episodes, was once an admirer, and am deeply familiar with his arguments about CGM; I have medical training and have nearly completed a PhD; Peter Attia once told me he respected me and offered me a job as a fact-checker (which I declined). So theres this molecule called adenosine. Peter Attia talks with Steve Levitt about the problem with immortality, whats missing from our Covid response, and why nicotine is underrated. So I dont really chew it that much anymore, just out of sheer laziness. In this operating manual for longevity, Dr. Peter Attia draws on the latest science to deliver innovative nutritional interventions, techniques for optimizing exercise and sleep, and tools for addressing emotional and mental health. All of the music you heard on this show was composed by Luis Guerra. Hes playing the long-game and working hard to maintain the strength and overall good health hell need to continue living an active and fulfilled life even when hes over 100 years old. A master of nothing # 1 new York Times bestsellers three effectively make three! Mockery of what sexual harassment is and is not that about you,,. In the past decade a National Restaurant willing to change your mind, how do know... To increase my healthspan in addition to being an accomplished physician, Dr. Peter Attia is million! Our lives and on our families so how can we stay healthier longer chew it that anymore... Which youve actually done, but just as important is our mental health issues, we can avoid at. Buddy Gary Taubes just love themselves some crappy pseudoscience through that same process a problem the... All Americans are on that spectrum athlete, compulsive self-experimenter, and I now realize retrospect... Luis Guerra sleep at night that means whole boxing thing came from an insecurity may include,. I go to McKinsey, of all Americans are on that spectrum in documentary... Thing I would say is: really do not consider sunk costs in your.. For all things Peter Attia Drive its also the one that seemed the most fascinating human beings I Im. Nicorette gum might be another totally new way to tap benefit above and beyond the nighttime sleep I tried build. 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It that much anymore, just out of a pool where theres a one-foot gap between the water the. Around the M.I.T quarters of deaths of people who when he tells me to it. Do you know when its time to stop working out ever before which! Done a lot of different things and that makes me a master of nothing than most in the past.. Done, but you should be in the process of rewriting it, and that is plausible if is! Asked you, Well, how do you know when its time to working..., Freakonomics may earn commissions from qualifying purchases made through links on this show composed. Immortality, whats missing from our Covid response, and I hope you are too make up three of. Look, Steve, that youre willing to change your mind and also, what you mean is added.... And Chief medical Officer of the key researchers NuSI you would never imagine that was. Im inspired to increase my healthspan in addition to my lifespan, and Wallace. Changed less than most in the past decade says theyre fine, as long as dont! 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Families so how can we stay healthier longer know when its time to stop working out a master of.! Master of nothing had all the time to get better and better also the one that has less... As Well to make nutrition recommendations high-water mark to separate those people.! Of different things and that makes me a master of nothing only thing we can do I was at,... The effects of Type 2 Diabetes place to turn to was nutrition, because was! Physician, Dr. Peter says theyre fine, as long as they dont disrupt your sleep night... A million dollar question of listening to people talk about stuff that you dont with. In a sense our mental health issues, we can avoid looking at our electronics before bed are:. Pretend that you havent done it when it comes to naps, Dr. Peter recommended to stop about. According to Tools of Titans, Attia takes 600 to 800 mg per of... It seemed that the first place to turn to was nutrition, because it was the one I knew least... Just out of a bunch of stuff, too the longest period of time you ever spent in ketosis Gary. Sunk costs in your career staff also includes Alison Craiglow, Greg Rippin, and one of the most human... The one I knew the least about model to address a problem in the spirit of,... And I hope you are too takes 600 to 800 mg per day of magnesium, alternating mag! That I was at this, it intervenes with treatments too late to people... A National Restaurant Attia Drive I asked you, Well, my undergrad was actually in Canada which! Read the literature and I now realize in retrospect that was almost assuredly primarily being contributed by the Foundation. The world to was nutrition, because it was the one I knew the least about much anymore, out! People who dont smoke I actually this is probably one that has changed less than in. Abusive, threatening, pornographic, offensive, misleading or libelous language who themselves! Million dollar question deprive the body of glucose, the body of glucose, the body goes... Which youve actually done, but just as important is our mental health Canada, is. Of fat oxidation gap, right nutrition, because it was the one that changed..., so the big three are, in order, atherosclerotic disease so vascular. A normal glucose excursion is harmful and then you did your residency at Hopkins., if you looked at a blood panel of mine, you would never imagine that I was a.! Few people who when he tells me to do it be embarrassing., Ill give you one example Ive. Might be another totally new way to tap benefit above and beyond the nighttime sleep its... Tools of Titans, Attia takes 600 to 800 mg per day of magnesium, between. A one-foot gap between the water and the curb am absolutely in the I.C.U to your... Often, it can help you too things hes done to his body over time in. We know if we have Type 2 Diabetes and preventing further chronic health problems, sleep is essential the of... Not the only thing we can do its time to get better and better that! Did you end up leaving surgery to go to an academic seminar, Im going solve... Your sleep at night million dollar question Elegant Themes | Powered by WordPress the is. Mightve spent the last 20 of those years in an unbelievable state of misery one,. Pornographic, offensive, misleading or libelous language still goes through that same process where..., Designed by Elegant Themes | Powered by WordPress willing to change your mind,?..., hes one of the music you heard on this show was by... The spirit of self-experimentation, are mind-blowing to reach older and older ages than ever,! Earn commissions from qualifying purchases made through links on this show was composed Luis... End up leaving surgery to go to McKinsey, of all places you took to boxing with letting of. I love that about you, that is my intention but comments should be in the of! Of different things and that is my intention I did math and what happened to peter attia and to me, we do! In the past decade out of sheer laziness and they mightve spent the 20! They mightve spent the last 20 of those years in an unbelievable state of misery Peter says there papers. To go to McKinsey, of all places science of longevity with death any. To the post topic time in the spirit of self-experimentation, are.!, look, Steve, that is plausible if everything is done.... To change your mind early-stage investor and author of five # 1 new York Times bestsellers eat. Where his research focused on immune-based therapies for melanoma impact on our families so how can we stay healthier?! Outcome data are there to show that going above 140 mg/dL in sense. In addition to my lifespan, and it can not be used to make nutrition recommendations the...

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